Can the prosocial benefits of episodic simulation transfer to different people and situational contexts?

Previous research has found that episodic simulation of events of helping others can effectively enhance intentions to help the same person involved and the identical situational context as the imagined scenarios. This 'prosocial simulation effect' is argued to reflect, at least in part, associative memory mechanisms whereby the simulation is reactivated when in the same situation as that imagined. However, to date, no study has examined systematically whether this 'prosocial simulation effect' can be transferred to response scenarios involving different people and/or situational contexts to the imagined scenarios, and if so, whether the degree of overlap with the imagined helping episode modulated the transfer effect. Across two experiments, we systematically varied the overlap of the simulated and response scenarios, both in terms of the persons in need and/or the situational contexts, and whether would influence the magnitude of prosocial simulation effect. Results from both experiments showed that the prosocial simulation effect can be transferred to response scenarios involving different people and situational contexts to the simulated scenarios. However, this finding was primarily driven by response scenarios that had a high degree of overlap to the simulated scenarios. The application of our findings to the practical implementation of simulation to promote prosociality in the real world is discussed.

Neural substrates of specific and general autobiographical memory retrieval in younger and older adults.

Healthy aging is associated with a shift away from the retrieval of specific episodic autobiographical memories (AMs), towards more general and semanticized memories. Younger adults modulate activity in the default mode network according to the episodic specificity of AM retrieval. However, little is known about whether aging disrupts this neural modulation. In the current study we examine age-related changes in the modulation of whole-brain networks in response to three tasks falling along a gradient of episodic specificity. Younger and older adults retrieved specific (unique) AMs, general (routine) AMs, and semantic (general knowledge) memories. We found that both younger and older adults modulated default mode regions in response to varying episodic specificity. In addition, younger adults upregulated activity in several default mode regions with increasing episodic specificity, while older adults either did not modulate these regions, or downregulated activity in these regions. In contrast, older adults upregulated activity in the left temporal pole for tasks with higher episodic specificity. These brain activation patterns converge with prior findings that specific AMs are diminished in episodic richness with age, but are supplemented with conceptual and general information. Age-related reductions in the modulation of default mode regions might contribute to the shift away from episodic retrieval and towards semantic retrieval, resulting in reduced episodic specificity of personal memories.

On pattern completion, cues and future-oriented cognition.

Barzykowski and Moulin's view on involuntary autobiographical memory focuses on automatic activation of representations and inhibitory control mechanisms. We discuss how and when a known neural mechanism - pattern completion - may result in involuntary autobiographical memories, the types of cues that may elicit this phenomenon and consider interactions with future-oriented cognition.

Thinking Beyond COVID-19: How Has the Pandemic Impacted Future Time Horizons?

Older age is reportedly protective against the detrimental psychological impacts of the COVID-19 pandemic, consistent with the theory that reduced future time extension (FTE) leads to prioritization of socioemotional well-being. We investigated whether depression severity and pandemic-related factors (regional severity, threat, social isolation) reduce FTE beyond chronological age and whether these relationships differ between younger and older adults. In May 2020, we recruited 248 adults (younger: 18-43 years, older: 55-80 years) from 13 industrialized nations. Multigroup path analysis found that depression severity was a better predictor of FTE than the reverse association in both age groups, suggesting an affective foreshortening of future time. In both age groups, older age was protective against depression severity, and younger age was associated with heightened vulnerability to the negative impacts of pandemic-related factors. Future research should consider the complex interrelationships between FTE, age, and depression severity and the potential impacts of the broader psychosocial milieu.

Short-sighted decision-making by those not vaccinated against COVID-19.

Widespread vaccination is necessary to minimize or halt the effects of many infectious diseases, including COVID-19. Stagnating vaccine uptake can prolong pandemics, raising the question of how we might predict, prevent, and correct vaccine hesitancy and unwillingness. In a multinational sample (N = 4,452) recruited from 13 countries that varied in pandemic severity and vaccine uptake (July 2021), we examined whether short-sighted decision-making as exemplified by steep delay discounting-choosing smaller immediate rewards over larger delayed rewards-predicts COVID-19 vaccination status. Delay discounting was steeper in unvaccinated individuals and predicted vaccination status over and above demographics or mental health. The results suggest that delay discounting, a personal characteristic known to be modifiable through cognitive interventions, is a contributing cause of differences in vaccine compliance.

Spatial variation of perfusion MRI reflects cognitive decline in mild cognitive impairment and early dementia.

Cerebral blood flow (CBF) measured with arterial spin labelling (ASL) magnetic resonance imaging (MRI) reflects cerebral perfusion, related to metabolism, and arterial transit time (ATT), related to vascular health. Our aim was to investigate the spatial coefficient of variation (sCoV) of CBF maps as a surrogate for ATT, in volunteers meeting criteria for subjective cognitive decline (SCD), amnestic mild cognitive impairment (MCI) and probable Alzheimer's dementia (AD). Whole-brain pseudo continuous ASL MRI was performed at 3 T in 122 participants (controls = 20, SCD = 44, MCI = 45 and AD = 13) across three sites in New Zealand. From CBF maps that included all grey matter, sCoV progressively increased across each group with increased cognitive deficit. A similar overall trend was found when examining sCoV solely in the temporal lobe. We conclude that sCoV, a simple to compute imaging metric derived from ASL MRI, is sensitive to varying degrees of cognitive changes and supports the view that vascular health contributes to cognitive decline associated with Alzheimer's disease.

Divergent thinking and constructing future events: dissociating old from new ideas.

Divergent thinking (the ability to generate creative ideas by combining diverse types of information) has been previously linked to the ability to imagine novel and specific future autobiographical events. Here, we examined whether divergent thinking is differentially associated with the ability to construct novel imagined future events and recast future events (i.e., actual past events recast as future events) as opposed to recalled past events. We also examined whether different types of creative ideas (i.e., old ideas from memory or new ideas from imagination) underlie the linkage between divergent thinking and various autobiographical events. Divergent thinking ability was measured using the Alternate Uses Task (AUT). In Experiment 1, the amount of episodic details for both novel and recast future events was associated with divergent thinking (AUT scores), and this relationship was significant with AUT scores for new creative ideas but not old creative ideas. There was no significant relationship between divergent thinking and the amount of episodic detail for recalled past events. We extended these findings in Experiment 2 to a different test of divergent thinking, the Consequences Task. These results demonstrate that individual differences in divergent thinking are associated with the capacity to both imagine and recast future events.

Getting better without memory.

Does the tendency to adjust appraisals of ourselves in the past and future in order to maintain a favourable view of ourselves in the present require episodic memory? A developmental amnesic person with impaired episodic memory (HC) was compared with two groups of age-matched controls on tasks assessing the Big Five personality traits and social competence in relation to the past, present and future. Consistent with previous research, controls believed that their personality had changed more in the past 5 years than it will change in the next 5 years (i.e. the end-of-history illusion), and rated their present and future selves as more socially competent than their past selves (i.e. social improvement illusion), although this was moderated by self-esteem. Despite her lifelong episodic memory impairment, HC also showed these biases of temporal self-appraisal. Together, these findings do not support the theory that the temporal extension of the self-concept requires the ability to recollect richly detailed memories of the self in the past and future.

Age-related changes in repetition suppression of neural activity during emotional future simulation.

Despite advances in understanding the consequences of age-related episodic memory decline for future simulation, much remains unknown regarding changes in the neural underpinnings of future thinking with age. We used a repetition suppression paradigm to explore age-related changes in the neural correlates of emotional future simulation. Younger and older adults simulated positive, negative, and neutral future events either 2 or 5 times. Reductions in neural activity for events simulated 5 versus 2 times (i.e., repetition suppression) identify brain regions responsive to the specific emotion of simulated events. Critically, older adults showed greater repetition suppression than younger adults in the temporal pole for negative simulations, and the cuneus for positive simulations. These findings suggest that older adults distance themselves from negative future possibilities by thinking about them in a more semantic way, consistent with the view that older adults down-regulate negative affect and up-regulate positive affect. More broadly this study increases our understanding of the impact of aging on the neural underpinnings of episodic future simulation.

Creative, internally-directed cognition is associated with reduced BOLD variability.

In a range of externally-directed tasks, intra-individual variability of fMRI BOLD signal has been shown to be a stronger predictor of cognitive performance than mean BOLD signal. BOLD variability's strong association with cognitive performance is hypothesised to be due to it capturing the dynamic range of neural systems. Although increased BOLD variability is also speculated to play a role in internally-directed thought, particularly when creative and flexible cognition is required, there is a relative lack of research exploring whether BOLD variability is related to internally-directed cognition. Thus, we investigated the relationship between BOLD variability and a key component of creativity - divergent thinking - in various tasks that required participants to think flexibly. We also determined whether any associations between BOLD variability and creativity overlapped with, or differed, from associations between mean BOLD signal and creativity. First, we performed task Partial Least Squares (PLS) analyses that compared BOLD signal (either mean or variability) during two future imagination conditions that differed in the amount of cognitive flexibility required: a Congruent condition in which autobiographical details (people, places, objects) comprising an imagined event belonged to the same social sphere (e.g., university) and an Incongruent condition in which details belonged to different social spheres and required greater cognitive flexibility to integrate. Results indicated that the Incongruent condition was associated with a widespread reduction in both BOLD variability and mean signal (relative to the Congruent condition), but in largely non-overlapping regions. Next, we used behavioral PLS to determine whether individual differences in performance on future simulation tasks as well as the Alternate Uses Task relates to BOLD variability and mean BOLD signal. Better performance on these tasks was predominantly associated with increases in mean BOLD signal and decreases in BOLD variability, in a range of disparate brain regions. Together, the results suggest that, unlike tasks requiring externally-directed cognition, superior performance on tasks requiring creative internal mentation is associated with less (not more) variability.

Relational processing demands and the role of spatial context in the construction of episodic simulations.

Reports on differences between remembering the past and imagining the future have led to the hypothesis that constructing future events is a more cognitively demanding process. However, factors that influence these increased demands, such as whether the event has been previously constructed and the types of details comprising the event, have remained relatively unexplored. Across two experiments, we examined how these factors influence the process of constructing event representations by having participants repeatedly construct events and measuring how construction times and a range of phenomenological ratings changed across time points. In Experiment 1, we contrasted the construction of past and future events and found that, relative to past events, the constructive demands associated with future events are particularly heightened when these events are imagined for the first time. Across repeated simulations, future events became increasingly similar to past events in terms of construction times and incorporated detail. In Experiment 2, participants imagined future events involving two memory details (person, location) and then reimagined the event either (a) exactly the same, (b) with a different person, or (c) in a different location. We predicted that if generating spatial information is particularly important for event construction, a change in location will have the greatest impact on constructive demands. Results showed that spatial context contributed to these heightened constructive demands more so than person details, consistent with theories highlighting the central role of spatial processing in episodic simulation. We discuss the findings from both studies in the light of relational processing demands and consider implications for current theoretical frameworks. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Reinstatement of Event Details during Episodic Simulation in the Hippocampus.

According to the constructive episodic simulation hypothesis, episodic simulation (i.e., imagining specific novel future episodes) draws on some of the same neurocognitive processes that support episodic memory (i.e., recalling specific past episodes). Episodic retrieval supports the ability to simulate future experiences by providing access to episodic details (e.g., the people and locations that comprise memories) that can be recombined in new ways. In the current functional neuroimaging study, we test this hypothesis by examining whether the hippocampus, a region implicated in the reinstatement of episodic information during memory, supports reinstatement of episodic information during simulation. Employing a multivoxel pattern similarity analysis, we interrogated the similarity between hippocampal neural patterns during memory and simulation at the level of individual event details. Our findings indicate that the hippocampus supports the reinstatement of detail-specific information from episodic memory during simulation, with the level of reinstatement contributing to the subjective experience of simulated details.

Specificity of Future Thinking in Depression: A Meta-Analysis.

Reduced specificity of autobiographical memory has been well established in depression, but whether this overgenerality extends to future thinking has not been the focus of a meta-analysis. Following a preregistered protocol, we searched six electronic databases, Google Scholar, and personal libraries and contacted authors in the field for studies matching search terms related to depression, future thinking, and specificity. We reduced an initial 7,332 results to 46 included studies, with 89 effect sizes and 4,813 total participants. Random-effects meta-analytic modeling revealed a small but robust correlation between reduced future specificity and higher levels of depression (r = -.13, p < .001). Of the 11 moderator variables examined, the most striking effects were related to the emotional valence of future thinking (p < .001) and the sex of participants (p = .025). Namely, depression was linked to reduced specificity for positive (but not negative or neutral) future thinking, and the relationship was stronger in samples with a higher proportion of males. This meta-analysis contributes to our understanding of how prospection is altered in depression and dysphoria and, by revealing areas where current evidence is inconclusive, highlights key avenues for future research.

Neural Mechanisms of Episodic Retrieval Support Divergent Creative Thinking.

Prior research has indicated that brain regions and networks that support semantic memory, top-down and bottom-up attention, and cognitive control are all involved in divergent creative thinking. Kernels of evidence suggest that neural processes supporting episodic memory-the retrieval of particular elements of prior experiences-may also be involved in divergent thinking, but such processes have typically been characterized as not very relevant for, or even a hindrance to, creative output. In the present study, we combine functional magnetic resonance imaging with an experimental manipulation to test formally, for the first time, episodic memory's involvement in divergent thinking. Following a manipulation that facilitates detailed episodic retrieval, we observed greater neural activity in the hippocampus and stronger connectivity between a core brain network linked to episodic processing and a frontoparietal brain network linked to cognitive control during divergent thinking relative to an object association control task that requires little divergent thinking. Stronger coupling following the retrieval manipulation extended to a subsequent resting-state scan. Neural effects of the episodic manipulation were consistent with behavioral effects of enhanced idea production on divergent thinking but not object association. The results indicate that conceptual frameworks should accommodate the idea that episodic retrieval can function as a component process of creative idea generation, and highlight how the brain flexibly utilizes the retrieval of episodic details for tasks beyond simple remembering.

The Persistence of the Self over Time in Mild Cognitive Impairment and Alzheimer's Disease.

Diachronic unity is the belief that, despite changes, we are the same person across the lifespan. We propose that diachronic unity is supported by the experience of remembering the self over time during episodic recall (i.e., phenomenological continuity). However, we also predict that diachronic unity is also possible when episodic memory is impaired, as long as the ability to construct life narratives from semantic memory (i.e., semantic continuity) is intact. To examine this prediction, we investigated diachronic unity in Alzheimer's Disease (AD) and amnestic mild cognitive impairment (aMCI), two conditions characterised by disrupted phenomenological continuity. If semantic continuity is also altered in these conditions, there should be an associated deterioration in diachronic unity. Participants with AD, aMCI, and healthy controls (HC) completed a self-persistence interview measuring diachronic unity (beliefs about self-persistence, explanations for stability/change). Semantic continuity was assessed with a life-story interview measuring autobiographical reasoning (self-event connections), and coherence (temporal/thematic/causal) of narratives. Our results highlight a complex relationship between semantic continuity and diachronic unity and revealed a divergence between two aspects of diachronic unity: AD/aMCI groups did not differ from HC in continuity beliefs, but AD explanations for self-persistence were less sophisticated. Semantic continuity was most impaired in AD: their narratives had fewer self-event connections (vs. HCs) and lower temporal/thematic coherence (vs. HC/aMCI), while both AD/aMCI groups had lower causal coherence. Paradoxically AD participants who scored higher on measures of beliefs in the persistence of the core self, provided less sophisticated explanations for their self-persistence and were less able to explore persistence in their life narratives. These findings support the importance of semantic continuity to diachronic unity, but suggest a more nuanced and multifaceted relationship than originally proposed in our model. In AD, diminished life narratives that retain features of cultural life scripts are sufficient for strong subjective beliefs of self-persistence, but not for sophisticated explanations about persistence. Better semantic continuity, with the ability to weave high-quality life narratives, may scaffold the capacity to understand and explain one's diachronic unity, but this produces less surety about self-persistence.

Constructive episodic simulation, flexible recombination, and memory errors.

According to Mahr & Csibra (M&C), the view that the constructive nature of episodic memory is related to its role in simulating future events has difficulty explaining why memory is often accurate. We hold this view, but disagree with their conclusion. Here we consider ideas and evidence regarding flexible recombination processes in episodic retrieval that accommodate both accuracy and distortion.

Scene Construction and Relational Processing: Separable Constructs?

Imagining hypothetical events often entails the construction of a detailed mental simulation. Despite recent advances, debate still surrounds the fundamental constructive process underpinning simulations supported by the hippocampus. Palombo et al. (2016) report findings that suggest that scene construction drives hippocampal engagement during imagination. However, they fail to consider the findings of a previous study using an extremely similar manipulation that generated similar hippocampal findings, but was interpreted in terms of event specificity and relational processing (Addis et al. 2011). While we applaud the general approach taken by Palombo et al. in attempting to distinguish components of mental simulation, a comparison of these 2 papers has brought into sharp relief how the lack of a common theoretical framework can result in significant interpretative ambiguities. In this commentary, we attempt to identify and clarify these as yet unresolved conceptual issues that will require empirical and theoretical attention in future research.

Forget about the future: effects of thought suppression on memory for imaginary emotional episodes.

Whether intentional suppression of an unpleasant or unwanted memory reduces the ability to recall that memory subsequently is a contested issue in contemporary memory research. Building on findings that similar processes are recruited when individuals remember the past and imagine the future, we measured the effects of thought suppression on memory for imagined future scenarios. Thought suppression reduced the ability to recall emotionally negative scenarios, but not those that were emotionally positive. This finding suggests that intentionally avoiding thoughts about emotionally negative episodes may inhibit representations of those memories, progressively reducing their availability to recall.

Episodic and semantic content of memory and imagination: A multilevel analysis.

Autobiographical memories of past events and imaginations of future scenarios comprise both episodic and semantic content. Correlating the amount of "internal" (episodic) and "external" (semantic) details generated when describing autobiographical events can illuminate the relationship between the processes supporting these constructs. Yet previous studies performing such correlations were limited by aggregating data across all events generated by an individual, potentially obscuring the underlying relationship within the events themselves. In the current article, we reanalyzed datasets from eight studies using a multilevel approach, allowing us to explore the relationship between internal and external details within events. We also examined whether this relationship changes with healthy aging. Our reanalyses demonstrated a largely negative relationship between the internal and external details produced when describing autobiographical memories and future imaginations. This negative relationship was stronger and more consistent for older adults and was evident both in direct and indirect measures of semantic content. Moreover, this relationship appears to be specific to episodic tasks, as no relationship was observed for a nonepisodic picture description task. This negative association suggests that people do not generate semantic information indiscriminately, but do so in a compensatory manner, to embellish episodically impoverished events. Our reanalysis further lends support for dissociable processes underpinning episodic and semantic information generation when remembering and imagining autobiographical events.